UNIT 7
LESSON: MOLECULAR BASIS OF INHERITANCE
Topics for Board 2019
1.
Structure of Nucleosomes
DNA vs RNA
3.
Hershey Chase Experiment
4.
Replication: key points
5.
Meselson & Stahl Experiment
6.
Transcription Unit (diagram & Key Points)
7.
Transcription: Prokaryotes vs Eukaryotes
8.
Translation: Key Points
9.
Regulation of gene expression: Lac operon
10.
DNA Fingerprinting
11.
Human genome Project
1. Nucleosomes
Key Features:
- DNA (200 bp) + Histone Octamer → Nucleosomes + H1 histone → Chromatin
- Histone: positively charged Protein (rich in Lysine & arginine)
- Histone octamer made of 8 subunits
- Chromatin packed with help of NHC (non-histone chromosomal proteins) - SCAFFOLDING
